Studies on aromatase inhibitors IV. Synthesis and biological evaluation of N,N-disubstituted-5-aminopyramidine derivatives

DOI: 10.1248/cpb.45.1293

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1293 - 1299 (1997)

Update date:2022-08-04

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Authors:

Okada, Minoru

Yoden, Toru

Kawaminami, Eiji

Shimada, Yoshiaki

Kudoh, Masafumi

Isomura, Yasuo

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Article abstract of DOI:10.1248/cpb.45.1293

In order to study the potency of the 5-aminopyrimidine skeleton as an aromatase inhibitor, we synthesized various N,N-disubstituted-15- aminopyrimidine derivatives and evaluated their aromatase-inhibitory activity (in vitro) and their inhibitory activity

Full text of DOI:10.1248/cpb.45.1293

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