Structural Evolution and Pharmacology of a Novel Series of Triacid Angiotensin II Receptor Antagonists

DOI: 10.1021/jm00052a010

Source and publish data:

Journal of Medicinal Chemistry p. 4508 - 4521 (1994)

Update date:2022-08-02

Topics:

Authors:

Palkowitz, Alan D.

Steinberg, Mitchell I.

Thrasher, K. Jeff

Reel, Jon K.

Hauser, Kenneth L.

et al. et al.

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Article abstract of DOI:10.1021/jm00052a010

cis-4-(4-Phenoxy)-1-<1-oxo-2(R)-<4-<(2-sulfobenzoyl)amino>-1H-imidazol-1-yl>octyl>-L-proline derivatives represent a novel class of potent nonpeptide angiotensin II (Ang II) receptor antagonists.These compounds evolved from directed structure-activity rel

Full text of DOI:10.1021/jm00052a010

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