Lasonolide A: Structural revision and total synthesis

DOI: 10.1021/jo034930n

Source and publish data:

Journal of Organic Chemistry p. 8080 - 8087 (2003)

Update date:2022-07-29

Topics: Total synthesis Chemical Structure Biological Activity Natural product Structural revision

Authors:

Song, Ho Young

Joo, Jung Min

Kang, Jung Won

Kim, Dae-Shik

Jung, Cheol-Kyu

Kwak, Hyo Shin

Park, Jin Hyun

Lee, Eun

Hong, Chang Yong

Jeong, ShinWu

Jeon, Kiwan

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Article abstract of DOI:10.1021/jo034930n

The proposed structure of lasonolide A was synthesized employing radical cyclization reactions of β-alkoxyacrylates for preparation of the tetrahydropyranyl units A and B, but the spectroscopic data did not match those of the natural product. Both enantio

Full text of DOI:10.1021/jo034930n

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