Synthesis, conformation, and glycosidic coupling reactions of highly active substituted 2,7-dioxabicycloheptanes: 1,2-anhydro-3,4-di-O-benzyl-α-D-xylopyranose

Article abstract of DOI:10.1016/0008-6215(94)84074-1

The title 1,2-anhydro sugar (8) was synthesized from D-xylose.The key intermediate for the synthesis was 2-O-acetyl-3,4-di-O-benzyl-β-D-xylopyranosyl fluoride, which was transformed into crystalline 8 by ring closure with potassium tert-butoxide.Compariso