
Tetrahedron p. 7321 - 7330 (1995)
Update date:2022-09-26
Topics:
Boyce, Richard J.
Mulqueen, Gerard C.
Pattenden, Gerald
The total synthesis of the cinnamyl-oxazole substituted tris-thiazoline containing metabolite (-)-thiangazole (1) is described. The synthesis is based on elaboration of the R-2-methylcysteine derived bis-thiazoline nitrile (5) and oxazole (6) intermediate
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