Facile Synthesis of (+)-Brefeldin A Utilizing Two Optically Active Synthons Prepared by Different Enzyme-catalysed Reactions

DOI: 10.1039/c39940001085

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1085 - 1086 (1994)

Update date:2022-08-05

Topics: Optically active Facile Synthesis Synthons (+)-Brefeldin A

Authors:

Casy, Guy

Gorins, Gilles

McCague, Ray

Olivo, Horacio F.

Roberts, Stanley M.

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Article abstract of DOI:10.1039/c39940001085

The lactone 4a and the alcohol 6 (both available in optically active form from biocatalytic processes) have been used as synthons in the preparation of (+)-brefeldin A.

Full text of DOI:10.1039/c39940001085

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