A short route to avenaciolide & isoavenaciolide via radical cyclization

Article abstract of DOI:10.1016/S0040-4039(00)78198-6

The bicyclic ether/lactone 5 was prepared from 7 in 6 steps including radical cyclization and a Pummerer rearrangement. After 5 was converted to 12 and 13 under Keek's conditions, divergent formal total syntheses of avenaciolide and isoavenaciolide were a