A convenient preparation of optically pure 3-hydroxyglutaric acid derivatives

DOI: 10.1016/S0040-4039(00)73032-2

Source and publish data:

Tetrahedron Letters p. 1999 - 2002 (1994)

Update date:2022-07-31

Topics: Enantiomer Derivatives Optically pure Compound Cellular metabolism Preparation Chemical Reaction Convenient dicarboxylic acid

Authors:

Leclerc Leclerc

Uguen Uguen

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Article abstract of DOI:10.1016/S0040-4039(00)73032-2

The diastereomeric monoamides resulting from condensation of (L)-cysteine with 3-hydroxyglutarodinitrile have been separted by chromatography then transformed in a few steps into either (+) or (-) methyl ester of 4-cyano-3-hydroxybutyric acid.

Full text of DOI:10.1016/S0040-4039(00)73032-2

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