Journal of the Chemical Society. Chemical communications p. 2613 - 2614 (1994)
Update date:2022-08-04
Topics:
Mitchinson, Andrew
Golding, Bernard T.
Griffin, Roger J.
O'Sullivan, Mary C.
Agmatine and hirudonine, guanidine derivatives of putrescine and spermidine, respectively, are synthesised by the application of a new protecting group strategy for polyamines, which uses N-nitroguanidinyl as a precursor of guanidine functions and selectively blocks spermidine at N-1 and N-8 with trifluoroacetyl and at N-4 by 4-azidobenzyloxycarbonyl.
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