A Simple Enzymatic Synthesis of (3S,4R)-(+)-4-Hydroxy-3-phenyltetrahydroisoquinolines

DOI: 10.1016/0957-4166(94)80127-4

Source and publish data:

Tetrahedron Asymmetry p. 1567 - 1578 (1994)

Update date:2022-08-04

Topics:

Authors:

Tellitu, Imanol

Badia, Dolores

Dominguez, Esther

Garcia, Francisco J.

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Article abstract of DOI:10.1016/0957-4166(94)80127-4

An efficient versatile method is presented for the stereospecific synthesis of (+)-4-hydroxy-3-phenyltetrahydroisoquinolines 11 and 12 using (R)-arylcyanohydrins as the chiral starting material.From this asymmetric core, the synthetic process proceeds wit

Full text of DOI:10.1016/0957-4166(94)80127-4

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Product name:(1'S,2'R)-(-)-N-<2-(tert-butyldiphenylsilyloxy)-2-(3-methoxyphenyl)-1-phenylethyl>formamide

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