ASYMMETRIC SYNTHESIS OF DIFLUOROCYCLOPROPANES

DOI: 10.1016/0957-4166(94)80101-0

Source and publish data:

Tetrahedron Asymmetry p. 1423 - 1426 (1994)

Update date:2022-09-26

Topics:

Authors:

Taguchi, Takeo

Shibuya, Akira

Sasaki, Hirofumi

Endo, Jun-ichi

Morikawa, Tsutomu

Shiro, Motoo

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Article abstract of DOI:10.1016/0957-4166(94)80101-0

A highly diastereoselective synthesis of functionalized trans gem-difluorocyclopropane carboxylate 3 was achieved through sequential Michael addition of lithium enolate of homochiral N-acylimidazolidinone 2 with 2,4,6-trimethylphenyl (TMP) 4-bromo-4,4-dif

Full text of DOI:10.1016/0957-4166(94)80101-0

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