A novel class of inhibitors for human and rat steroid 5α-Reductases: Synthesis and biological evaluation of indoline and aniline derivatives. III

DOI: 10.1248/cpb.48.1689

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Chemical and Pharmaceutical Bulletin p. 1689 - 1697 (2000)

Update date:2022-08-05

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Authors:

Igarashi

Inami Inami

Hara Hara

Koutoku Koutoku

Oritani Oritani

Mase Mase

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Article abstract of DOI:10.1248/cpb.48.1689

While searching for novel nonsteroidal inhibitors of human and rat prostatic 5α-reductases, we found a new series of indoline and aniline derivatives that showed potent inhibitory activities for both enzymes. Among them, 3-chloro-4-{[1-(4-phenoxybenzyl)in

Full text of DOI:10.1248/cpb.48.1689

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