A novel class of inhibitors for human and rat steroid 5α-Reductases: Synthesis and biological evaluation of indoline and aniline derivatives. III

DOI: 10.1248/cpb.48.1689

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1689 - 1697 (2000)

Update date:2022-08-05

Topics:

Authors:

Igarashi

Inami Inami

Hara Hara

Koutoku Koutoku

Oritani Oritani

Mase Mase

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.48.1689

While searching for novel nonsteroidal inhibitors of human and rat prostatic 5α-reductases, we found a new series of indoline and aniline derivatives that showed potent inhibitory activities for both enzymes. Among them, 3-chloro-4-{[1-(4-phenoxybenzyl)in

Full text of DOI:10.1248/cpb.48.1689

NII-Electronic Library Service

Products guided by the article

Product name:4-(4-anilinophenoxy)-3-chlorobenznitrile

Cas No:158769-75-6

R&D Labs maybe for 158769-75-6

SHUNYUANSHENG BIO-PHARMTECH CO., LTD

website:https://www.whsysbio.com

Contact:--

Address:Building 13, Liandong U Valley-Wuhan Economic Innovation Valley, No. 259, Xingsan Road, Shamao Street, Hannan District, Wuhan City, Hubei Province
Hangzhou Fandachem Co.,Ltd

Contact:+86-158-5814-5714

Address:No.9 YanAn Road,Hangzhou,Zhejiang,China
Angel Yeast Co., Ltd.

Contact:+86-717-6370352

Address:168 Chengdong Avenue, Yichang, Hubei 443003, P. R.China
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Zibo Fuxi'er Chemical Co.,Ltd （Shanxian Fuxi'er Chemical Co.,Ltd）

Contact:+86-533-2091422

Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China

Relevant to this article

Dynamic Kinetic Resolution of Allylic Azides via Asymmetric Dihydroxylation

Doi:10.1021/jacs.7b04203
(2017)
First chemical synthesis report of an anthocyanin metabolite with in vivo occurrence: Cyanidin-4′-O-methyl-3-glucoside

Doi:10.1016/j.tetlet.2013.03.100
(2013)
Aminoethyl-functionalized cyclopentadienyliridium complexes: Photochemical C-H activation and carbonylation of cycloalkanes

Doi:10.1002/ejic.200501049
(2006)
Synthesis and antiviral evaluation of halogenated β-D- and -L- erythrofuranosylbenzimidazoles

Doi:10.1021/jm990195p
(2000)
A New Route to the Improved Synthesis of 1-(Alkoxymethyl)-5-alkyl- 6-(arylselenenyl)uracils

Doi:10.1002/jhet.5570340252
(1997)
Synthesis of poly(para-phenylene)(2-isocyano-2-tosylpropane-1,3-diyl), poly(para-phenylene)(2-oxopropane-1,3-diyl) and oligo(cyclopentadienones) via carbonylative coupling of α,α′-dibromoxylene

Doi:10.1039/b706807g
(2007)

Article Doi