Synthesis of novel β-lactam core structures related to the penam and penem antibiotics

DOI: 10.1021/jo00099a007

Source and publish data:

Journal of Organic Chemistry p. 5858 - 5861 (1994)

Update date:2022-08-03

Topics:

Authors:

Ren Ren

Turos Turos

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Article abstract of DOI:10.1021/jo00099a007

The synthesis of a structurally new class of penicillin- and penem-type ring systems is described which is based on a sequential imine-ketene cycloaddition reaction and halogen-induced sulfide cyclization process.

Full text of DOI:10.1021/jo00099a007

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