Acylaminoacetyl derivatives of active methylene compounds. 4. Synthesis of N-protected tetramic acids via the C-acylation reaction of Meldrum's acid with the imidazolides of N-protected glycines

Article abstract of DOI:10.1002/jhet.5570330347

Meldrum's acid has been found to be effectively acylated using the imidazolides of N-protected glycines, X-NHCH₂COOH (X = -COPh, -COMe, -Z, -Boc, -COOMe and -COOEt). The corresponding C-acylation compounds were isolated in high yields and were