Identification and characterization of small molecule modulators of the epstein-barr virus-induced gene 2 (EBI2) receptor

DOI: 10.1021/jm4019355

Source and publish data:

Journal of Medicinal Chemistry p. 3358 - 3368 (2014)

Update date:2022-08-03

Topics:

Authors:

Gessier, Francois

Preuss, Inga

Yin, Hong

Rosenkilde, Mette M.

Laurent, Stephane

Endres, Ralf

Chen, Yu A.

Marsilje, Thomas H.

Seuwen, Klaus

Nguyen, Deborah G.

Sailer, Andreas W.

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Article abstract of DOI:10.1021/jm4019355

Oxysterols have recently been identified as natural ligands for a G protein-coupled receptor called EBI2 (aka GPR183) (Nature 2011, 475, 524; 519). EBI2 is highly expressed in immune cells (J. Biol. Chem. 2006, 281, 13199), and its activation has been sho

Full text of DOI:10.1021/jm4019355

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