
Journal of the Chemical Society. Perkin transactions I p. 2621 - 2624 (1994)
Update date:2022-08-04
Topics:
Park, Ki Hun
Yoon, Yong Jin
Lee, Sang Gyeong
A short and efficient synthesis of (-)-deoxymannojirimycin and (2S,3R,4R,5R)-3,4,5-trihydroxypipecolic acid is described with D-glucono-δ-lactone as chiral educt.Key transformations included selective cleavage of a terminal isopropylidene group with Dowex 50W-X8 (H+) and intramolecular nucleophilic amination.
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