4-(β-D-Ribofuranosyl)pyridazines: Novel C-nucleosides by [4+2]-cycloadditions with inverse electron demand

Article abstract of DOI:10.1002/ardp.19943270604

A route for synthesizing novel C-nucleosides with 3,6- and 3,5,6-substituted pyridazines as heterocyclic aglycones is described. [4+2]-Cycloadditions of the alkyne substituted precursors 1 and 10a-d with the 1,2,4,5-tetrazines 2a,b, containing a highly re