A facile preparation of 2- and 5-substituted 3-bromothiophenes

DOI: 10.1016/S0040-4039(00)78549-2

Source and publish data:

Tetrahedron Letters p. 9387 - 9390 (1994)

Update date:2022-09-26

Topics: Regioselectivity Column chromatography Catalyst Nucleophile Solvent Recrystallization Stirring Thiophene Bromination Isomer Workup Aromaticity Halogenation Reaction Monitoring Electrophilic Aromatic Substitution (EAS) Facile preparation Functional group Reaction yield NMR spectroscopy (Nuclear Magnetic Resonance)

Authors:

Masquelin

Obrecht Obrecht

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)78549-2

Acetylenic ketones of type 4 and acetylenic acetals of type 6 (Scheme 1) are excellent cyclization precursors for the acid-catalyzed synthesis of various heterocycles. Using this methodology, 5- and 2-substituted 3-bromothiophenes of types 7 and 8 have be

Full text of DOI:10.1016/S0040-4039(00)78549-2

Products guided by the article

Product name:4-Hexyn-3-one, 2,2-dimethyl-6-[(triphenylmethyl)thio]-

Cas No:160855-11-8

R&D Labs maybe for 160855-11-8

SINO GREAT ENTERPRISE LTD.

Contact:+86-731-84427351

Address:154 JIANXIANG SOUTH ROAD
SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD(expird)

Contact:+86-311-85208698 311-80837698

Address:NO.166, yuhua west road, SHIJIAZHUANG, China
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
Chongqing Rong＆Quan Pharmaceutical Technology Co. , Ltd.

Contact:86-023-65268721

Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

Investigation of putative arene-C-H?π(quasi-chelate ring) interactions in copper(i) crystal structures

Doi:10.1039/c4cc02040e
(2014)
Tandem deprotection-dimerization-macrocyclization route to C₂ symmetric cyclo-tetrapeptides

Doi:10.1002/chem.201304262
(2014)
Synthesis of Potential Heparanase Inhibitor

Doi:10.1246/cl.1994.2119
(1994)
HighlyZ-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thionesviaatom-specific 5-exo-digcyclization of propargyl alcohol with isothiocyanate

Doi:10.1039/d0ob00083c
(2020)
Visible-light-mediated addition of α-aminoalkyl radicals to [60]fullerene by using photoredox catalysts

Doi:10.1002/chem.201304731
(2014)
Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

Doi:10.1002/cbdv.202001037
(2021)

Article Doi