Tetrahedron Letters p. 9387 - 9390 (1994)
Update date:2022-09-26
Topics: Regioselectivity Column chromatography Catalyst Nucleophile Solvent Recrystallization Stirring Thiophene Bromination Isomer Workup Aromaticity Halogenation Reaction Monitoring Electrophilic Aromatic Substitution (EAS) Facile preparation Functional group Reaction yield NMR spectroscopy (Nuclear Magnetic Resonance)
Masquelin
Obrecht
Acetylenic ketones of type 4 and acetylenic acetals of type 6 (Scheme 1) are excellent cyclization precursors for the acid-catalyzed synthesis of various heterocycles. Using this methodology, 5- and 2-substituted 3-bromothiophenes of types 7 and 8 have be
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Doi:10.1039/c4cc02040e
(2014)Doi:10.1002/chem.201304262
(2014)Doi:10.1246/cl.1994.2119
(1994)Doi:10.1039/d0ob00083c
(2020)Doi:10.1002/chem.201304731
(2014)Doi:10.1002/cbdv.202001037
(2021)
