
Chemical and Pharmaceutical Bulletin p. 1609 - 1616 (1994)
Update date:2022-08-04
Topics:
Seki
Takezaki
Ohuchi
Ohuyabu
Ishimori
Yasuda
A series of hydrazinopyridazine derivatives combined with a β-blocking side chain were synthesized. When they were given intravenously to anesthetized rats, some of them exhibited both hypotensive and β-blocking activities. Their structure-activity relati
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