Tetrahedron Letters p. 9545 - 9548 (1994)
Update date:2022-08-05
Topics:
Benjahad, Abdellah
Benhaddou, Rachida
Granet, Robert
Kaouadji, Mourad
Krausz, Pierre
et al.
Glycosylation of 3-alkyl N4-(3-hydroxypropyl) 2-piperazinones by ptotected 1-O-acetyl ribofuranoses produces nucleoside analogs in which the base is separated from the sugar by a hydrocarbon spacer arm.The preliminary in vitro test results against retroviruses seem promising for compounds bearing a long alkyl chain.
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