Amidoalkylation of Aromatics with Glyoxylic Acid-γ-Lactam Adducts: 2-Pyrrolidinone, Pyroglutamic Acid Amide and Ester

DOI: 10.1016/0040-4020(94)00952-Q

Source and publish data:

Tetrahedron p. 801 - 810 (1995)

Update date:2022-08-03

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Authors:

Roth, Ecaterina

Altman, Janina

Kapon, Moshe

Ben-Ishai, Dov

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Article abstract of DOI:10.1016/0040-4020(94)00952-Q

A glyoxylic acid-2-pyrrolidinone adduct leads to N-acyliminium-ion induced intermolecular electrophilic aromatic substitution yielding nitrogen-substituted phenylglycine derivatives, whereas the benzylamide of glyoxylic acid-2-pirrolidinone adduct undergo

Full text of DOI:10.1016/0040-4020(94)00952-Q

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