Tetrahedron Asymmetry p. 245 - 254 (1995)
Update date:2022-08-03
Topics:
Morita
Otsubo
Matsubara
Ohtani
Uchida
An efficient and highly enantioselective synthesis of (S)-(-)-5,6-difluoro-2-methyl-1,2,3,4-tetrahydroquinoline (4b), a key intermediate in the synthesis of (S)-(-)-nadifloxacin (2), was carried out by using a cross-coupling reaction. Also α,β-acetylenic
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