Synthesis and hypolipidemic activity of N-pyridinyl borodipeptidylamides

Article abstract of DOI:10.1016/0223-5234(94)90111-2

A series of borodipeptide derivatives 7-9, which contain a 6-amino-2,4-dimethylpyridine moiety, was prepared in 3 steps.They were evaluated as hypolipidemic agents in rodents at 20 mg/kg per day.The methioninamide and phenylalaninamide derivatives were th