Nucleotides. Part XLIV. Synthesis, characterization, and biological activity of monomeric and trimeric cordycepin-cholesterol conjugates and inhibition of HIV-1 replication

DOI: 10.1002/hlca.19940770707

Source and publish data:

Helvetica Chimica Acta p. 1757 - 1767 (1994)

Update date:2022-07-30

Topics:

Authors:

Wasner Wasner

Henderson

Suhadolnik

Pfleiderer

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Article abstract of DOI:10.1002/hlca.19940770707

The antivirally active 3'-deoxyadenylyl-(2'-5')-3'-deoxyadenylyl-(2'-5')-3'-deoxyadenosine (cordycepin trimer core) was modified at the 2'- or 5'-terminus, by attachment of cholesterol via a carbonate bond (→15) or a succinate linker (→16 and 27) to impro

Full text of DOI:10.1002/hlca.19940770707

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