Journal of Natural Products p. 54 - 58 (1999)
Update date:2022-08-04
Topics:
Galal, Ahmed M.
Ahmad, M. Shamim
El-Feraly, Farouk S.
McPhail, Andrew T.
Reaction of artemisinin (1) with ammonia, methylamine, dimethylamine, and allylamine afforded five unexpected products 2-6, in addition to the previously reported compounds 7-12. The identities of the new compounds were established from their spectral data, by chemical derivatization and by comparison with published reports. The stereochemistries of compounds 5 and 6 were confirmed by single-crystal X-ray analysis.
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