Synthesis and evaluation of homoazasugars as glycosidase inhibitors

Article abstract of DOI:10.1021/jo00111a007

In an effort to develop transition-state mimetics of the glycosidase-catalyzed reaction, five- and six-membered azasugars and their homo-analogs were prepared and tested as inhibitors of glycosidases. Inhibition studies indicate that the fucosyl cationlik