Synthesis of taxol and taxotere side chains by 2-(trimethylsilyl)thiazole based homologation of L-phenylglycine

DOI: 10.1055/s-1995-3882

Source and publish data:

Synthesis p. 181 - 186 (1995)

Update date:2022-09-26

Topics:

Authors:

Dondoni Dondoni

Perrone Perrone

Semola Semola

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1995-3882

L-Phenylglycine is homologated by the use of 2-(trimethylsilyl)thiazole into (2R,3S)-N-benzoyl- and N-tert-butoxycarbonyl-3-phenylisoserine, which are isolated as acetonide derivatives in 47 and 35% overall yields and with 84 and 90% ee, respectively.

Full text of DOI:10.1055/s-1995-3882

Products guided by the article

Product name:2-<(4S,5R)-N-tert-butoxycarbonyl-2,2-dimethyl-4-phenyl-1,3-oxazolidin-5-yl>-1,3-thiazole

Cas No:163010-80-8

R&D Labs maybe for 163010-80-8

Oceachem Group Limited

website:http://www.oceanchem-group.com

Contact:86-536-8596048

Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Li's chemicals

Contact:+86-15850770348

Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
Global United Biotechnology Inc.

Contact:+86-21-61618568

Address:Room 309, Building 6, NO.135, Jinyu Road, Pudong
Shenzhen ZheYi Chemicals Co.,LTD(Shanghai Branch)

Contact:+86-21-54159691

Address:Room1002,Building No.2, Lane 98 Bixiu Road,Minhang District, Shanghai,China 201100

Relevant to this article

Asymmetric dihydroxylation of aryl allyl ethers

Doi:10.1016/S0040-4039(00)77590-3
(1993)
Synthesis of 1-(3-Phenoxyphenyl)butane-1,3-dione from ethyl acetoacetate

Doi:10.1134/S1070363213100253
()
Studies on chiral organosulfur compounds. VI. The use of a chiral diene bearing an optically active sulfinylmethyl group in the Lewis acid-catalyzed intramolecular asymmetric hetero Diels-Alder reaction

Doi:10.1248/cpb.45.759
(1997)
Synthesis of a 1,2-trans-Configurated, Equatorial Glycosylphosphonate Analogue of D-myo-Inositol 1,4,5-Trisphosphate

Doi:10.1002/hlca.19930760224
(1993)
Nucleic-Acid Analogues with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone ('Bicyclo-DNA'), Part 1. Preparation of (3'S,5'R)-2'-Deoxy-3',5'-ethano-αβ-D-ribonucleosides ('Bicyclonucleosides')

Doi:10.1002/hlca.19930760132
(1993)
Is the previously described N-phenyl 4,5-benzo 1,3,2-diazaphosphole a dicoordinated phosphorus compound ?

Doi:10.1016/S0040-4020(01)81293-X
(1993)

Article Doi