Structure-Activity Relationships of 9-Alkyladenine and Ribose-Modified Adenosine Derivatives at Rat A3 Adenosine Receptors

DOI: 10.1021/jm00010a017

Source and publish data:

Journal of Medicinal Chemistry p. 1720 - 1735 (1995)

Update date:2022-08-05

Topics: Structure-activity relationships Chemical Synthesis High-Throughput Screening Structure-activity relationship study Radioligand Binding Assay

Authors:

Jacobson, Kenneth A.

Siddiqi, Suhaib M.

Olah, Mark E.

Ji, Xiao-duo

Melman, Neli

et al. et al.

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Article abstract of DOI:10.1021/jm00010a017

9-Alkyladenine derivatives and ribose-modified N⁶-benzyladenosine derivatives were synthesized in an effort to identify selective ligands for the rat A₃ adenosine receptor and leads for the development of antagonists.The derivatives

Full text of DOI:10.1021/jm00010a017

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