Journal of the Chemical Society. Perkin Transactions 2 (2001) p. 1131 - 1139 (1996)
Update date:2022-07-30
Topics:
Durand, Xavier
Hudhomme, Pietrick
Khan, Jeffrey A.
Young, Douglas W.
In studies directed at discovering the absolute stereochemistry of the reaction catalysed by the enzyme glutamate γ-carboxylase, two independent stereoselective syntheses of (2S,4S)-5,5′-dihydroxy[5,5- 2H2]-leucine 4a and its (2S,4R)-diastereoisomer 4b have been developed. The first synthesis uses (2S)-pyroglutamic acid as starting material and provides (2S,4S)-5,5′-dihydroxy[5,5-2H2]leucine 4a, while the second starts with (2S,4R)-4-hydroxyproline and provides (2S,4R)-5,5′-dihydroxy[5,5-2H2]leucine 4b.
View MoreContact:+86-18653358619
Address:zibo
Changsha Yonta Industry Co., Ltd.
Contact:+ 86-731-8535 2228
Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Liao Cheng All Win Chemicals Co.,LTD
Contact:86+0635-2991582
Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China
website:http://www.truewingroup.com
Contact:86-311-66699812
Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
Contact:0792-8228321
Address:10TH Floor No.121 binjiang Road Xunyang District
Doi:10.1080/00397919508010790
(1995)Doi:10.1016/0040-4039(95)00022-5
(1995)Doi:10.1016/j.tetasy.2007.02.028
(2007)Doi:10.1039/j39670001866
(1967)Doi:10.2533/chimia.2014.436
(2014)Doi:10.1080/00304948.2015.1025014
(2015)
