Synthesis of (S)-2-Amino-3-(3-tert-butyl-5-oxo-2H-isoxazol-4-yl)propionic Acid

DOI: 10.1021/jo00115a039

Source and publish data:

Journal of Organic Chemistry p. 3184 - 3188 (1995)

Update date:2022-08-03

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Authors:

Atfani, Mohamed

Lubell, William D.

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Article abstract of DOI:10.1021/jo00115a039

An efficient method for synthesizing enantiopure isoxazole amino acids has been developed. (2S)-2-Amino-3-(3-tert-butyl-5-oxo-2H-isoxazol-4-yl)propionic acid (1) was synthesized in three steps from L-γ-methyl N-(9-(9-phenylfluorenyl)glutamate (2) in 46per

Full text of DOI:10.1021/jo00115a039

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