Immunospecific reduction of antioligonucleotide antibody-forming cells with a tetrakis-oligonucleotide conjugate (LJP 394), a therapeutic candidate for the treatment of lupus nephritis

DOI: 10.1021/jm00012a013

Source and publish data:

Journal of Medicinal Chemistry p. 2138 - 2144 (1995)

Update date:2022-09-26

Topics:

Authors:

Jones Jones

Barstad Barstad

Feild Feild

Hachmann

Hayag Hayag

Hill Hill

Iverson Iverson

Livingston

Palanki Palanki

Tibbetts

Courts Courts

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Article abstract of DOI:10.1021/jm00012a013

A discrete tetravalent conjugate, 7a (LJP 394), consisting of four oligonucleotides attached to a common carrier or platform was prepared. Single-stranded oligonucleotide 20-mers consisting of alternating deoxycytidine-deoxyadenosine nucleotides, (CA) View More

Full text of DOI:10.1021/jm00012a013

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