A facile synthesis of (2S,3R,4S)-4-amino-5-cyclohexyl-1-morpholino-2,3-pentanediol, the C-terminal compound of renin inhibitor BW-175

DOI: 10.1016/0040-4020(94)01107-B

Source and publish data:

Tetrahedron p. 2427 - 2434 (1995)

Update date:2022-08-03

Topics:

Authors:

Shi, Zhi-Cai

Lin, Guo-Qiang

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Article abstract of DOI:10.1016/0040-4020(94)01107-B

A facile synthesis of (2S, 3R, 4S)-4-amino-5-cyclohexyl-1-morpholino-2, pentanediol (ACMP), the C-terminal compounds of renin inhibitor BW-175 is described.

Full text of DOI:10.1016/0040-4020(94)01107-B

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Product name:(3S,4R)-3-trimethylsilyloxy-4-hydroxy-5-cyclohexyl-1-pentene

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