Bioorganic and Medicinal Chemistry Letters p. 1535 - 1540 (1996)
Update date:2022-08-03
Topics:
Dhar, T. G. Murali
Nakanishi, Hiroshi
Borden, Laurence A.
Gluchowski, Charles
SK and F 89976-A (3) is a potent GABA uptake inhibitor, with a flexible diphenylbutenyl side chain. Conformationally restrained analogues of this compound, 14, 16, 18 and 20 were designed and synthesized to study the conformational preferences for binding to cloned GABA transporters. We conclude from this study that SK and F 89976-A probably binds to the GABA transporter in its fully extended conformation.
View MoreFrapp's Chemical (NFTZ) Co.,Ltd
Contact:+86-576-86137892
Address:General Chamber of Commercial Building, 159 Wanchang Middle Road, Wenling, Zhejiang, China
Yurui(Shanghai)Chemical Co.,Ltd
Contact:0086 21-50456736
Address:No.3188 Xiupu Road,Shanghai
website:http://www.synchemie.com/
Contact:+86-574-87642758
Address:Room 901, Yinyi Bund Building, 132 Renmin Road
ChangZhou XiaQing Chemical Co., Ltd.
Contact:+86-519-88721665
Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province,China
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD
Contact:+86-576-88685096
Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
Doi:10.1039/CC9960000241
(1996)Doi:10.1246/bcsj.76.2191
(2003)Doi:10.1016/0022-328X(94)05196-I
(1995)Doi:10.1039/c3md00290j
(2014)Doi:10.1016/0020-1693(94)04373-4
()Doi:10.1002/adsc.201600887
(2016)