Reductive ring opening of oxygen-containing benzo-fused heterocycles by an arene-catalysed lithiation

Article abstract of DOI:10.1055/s-2004-815971

The reductive ring opening of phthalan and isochroman in a 8 mmol scale process, using a small excess of lithium (1.35 equiv) and a substoichiometric amount of DTBB (3 mol%), leads to functionalised organolithium compounds, which after reaction with (-)-m