Reaction of methyl 4,5-epoxy-(2E)-pentenoate with arenes. I. A facile synthesis of 4-aryl-5-hydroxy-(2E)-pentenoate derivatives

DOI: 10.1248/cpb.42.1590

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1590 - 1595 (1994)

Update date:2022-08-03

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Authors:

Ono Ono

Todoriki

Yamamoto

Akita Akita

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Article abstract of DOI:10.1248/cpb.42.1590

The reactivity of methyl 4,5-epoxy-(2E)-pentenoate (2) toward various aromatic nucleophiles in the presence of boron trifluoride etherate was examined. When benzene derivatives possessing an electron-donating substituent were employed, meta-substituted be

Full text of DOI:10.1248/cpb.42.1590

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