Bioorganic and Medicinal Chemistry Letters p. 2481 - 2486 (1996)
Update date:2022-08-03
Topics: Stereochemistry Substituent Position Aromatic Rings Functional Groups Ring Modifications Isosteres
Miller, William H.
Ali, Fadia E.
Bondinell, William E.
Callahan, James F.
Calvo, Raul R.
Eggleston, Drake S.
Haltiwanger, R. Curtis
Huffman, William F.
Hwang, Shing-Mei
Jakas, Dalia R.
Keenan, Richard M.
Koster, Paul F.
Ku, Thomas W.
Kwon, Chet
Newlander, Kenneth A.
Nichols, Andrew J.
Parker, Michael F.
Samanen, James M.
Southall, Linda S.
Takata, Dennis T.
Uzinskas, Irene N.
Valocik, Richard E.
Vasko-Moser, Janice A.
Wong, Angela S.
Yellin, Tobias O.
Yuan, Catherine C. K.
In an investigation of the contribution of N-1 to the binding, antiaggregatory, and oral activity in 3-oxo-1,4-benzodiazepine-2-acetic acid based GPIIb/IIIa antagonists, a series of 2-benzazepine analogs, wherein N-1 of the 1,4-benzodiazepine nucleus has
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