DECYCLOPROPYLATION OF 1-CYCLOPROPYL-4-HYDROXY-4-(2-METHYLPHENYL)PIPERIDINE N-OXIDE

DOI: 10.1016/0040-4039(95)00693-7

Source and publish data:

Tetrahedron Letters p. 3981 - 3984 (1995)

Update date:2022-07-31

Topics:

Authors:

Wang, You-Xiong

Castagnoli, Neal

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Article abstract of DOI:10.1016/0040-4039(95)00693-7

Treatment of 1-cyclopropyl-4-hydroxy-4-(2-methylphenyl)piperidine N-oxide with trifluoroacetic anhydride (TFAA) yields the corresponding descyclopropyl secondary amine in excellent yield.This reaction may serve as a model for the mechanism based inactivat

Full text of DOI:10.1016/0040-4039(95)00693-7

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