Synthesis of carbocyclic nucleosides from 2-azabicyclo[2.2.1]hept-5-en-3-ones: Sodium borohydride-mediated carbon-nitrogen bond cleavage of five- and six-membered lactams

DOI: 10.1248/cpb.39.1112

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1112 - 1122 (1991)

Update date:2022-08-05

Topics:

Authors:

Katagiri

Muto Muto

Nomura Nomura

Higashikawa

Kaneko Kaneko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.1112

Various carbocyclic ribofuranosyl nucleosides were stereoselectively synthesized through a small number of steps from 2-azabicyclo[2.2.1]hept-5-en-3-ones by the use of sodium borohydride-mediated C-N bond cleavage as a key step. Ready availability of a no

Full text of DOI:10.1248/cpb.39.1112

NII-Electronic Library Service

Products guided by the article

Product name:3-Oxo-2-aza-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid benzylamide

Cas No:167417-32-5

R&D Labs maybe for 167417-32-5

BOC Sciences

website:https://www.bocsci.com/

Contact:1-631-485-4226

Address:Ramsey Road
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province

Relevant to this article

An approach towards the development of progesterone antagonists: Synthesis of 7α/7β-aryl androstene derivatives

Doi:10.1016/0039-128X(95)00007-D
(1995)
Synthesis of the first 1,2,4-triazine C-nucleoside and its transformation to novel pyridine C-nucleosides by 'inverse' [4 + 2]-cycloaddition reactions

Doi:10.1002/ardp.19953280216
(1995)
Scavenging of fluorinated N,N′-dialkylureas by hydrogen binding: A novel separation method for fluorous synthesis

Doi:10.1021/ol016165+
(2001)
Synthesis of the pentacyclic skeleton of the aspidosperma alkaloids using rhodium carbenoids as reactive intermediates

Doi:10.1021/jo971424n
(1998)
An efficient preparation of the potent and selective pseudopeptide thrombin inhibitor, inogatran

Doi:10.1016/S0960-894X(97)00271-0
(1997)
Kinetics of intramolecular additions of the aminyl radicals to carbonyl groups and subsequent ring opening

Doi:10.1016/0040-4020(95)00459-L
(1995)

Article Doi