Synthesis of carbocyclic nucleosides from 2-azabicyclo[2.2.1]hept-5-en-3-ones: Sodium borohydride-mediated carbon-nitrogen bond cleavage of five- and six-membered lactams

DOI: 10.1248/cpb.39.1112

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1112 - 1122 (1991)

Update date:2022-08-05

Topics:

Authors:

Katagiri

Muto Muto

Nomura Nomura

Higashikawa

Kaneko Kaneko

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Article abstract of DOI:10.1248/cpb.39.1112

Various carbocyclic ribofuranosyl nucleosides were stereoselectively synthesized through a small number of steps from 2-azabicyclo[2.2.1]hept-5-en-3-ones by the use of sodium borohydride-mediated C-N bond cleavage as a key step. Ready availability of a no

Full text of DOI:10.1248/cpb.39.1112

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