3-Substituted-1,2,4-Oxadiazolin-5-one; A Useful Amidine Precursor and Protecting Group

Article abstract of DOI:10.1016/0040-4039(95)00755-2

5-Benzyloxy-1,2,4-oxadiazoles and 1,2,4-oxadiazolin-5-ones are useful precursors to, and protecting groups for the amidine moiety.The latter compounds are readily prepared from amidoximes or alternatively via cycloaddition of nitrile oxides to trichloroac