Phosphodiester hydrolysis by a new zinc(II) macrocyclic tetraamine complex with an alcohol pendant: Elucidation of the roles of ser-102 and zinc(II) in alkaline phosphatase

DOI: 10.1021/ja00137a002

Source and publish data:

Journal of the American Chemical Society p. 8304 - 8311 (1995)

Update date:2022-08-05

Topics: Alkaline Phosphatase

Authors:

Kimura, Eiichi

Kodama, Yorimitsu

Koike, Tohru

Shiro, Motoo

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Article abstract of DOI:10.1021/ja00137a002

A new benzyl alcohol-pendant 1,4,7,10-tetraazacyclododecane (cyclen) ligand, (S)-1-(2-hydroxy-2-phenylethyl)-1,4,7,10-tetraazacyclododecane (L) (11), has been synthesized. The complexation of 11 with Zn^II yielded 1:1 five-coordinate complexes (

Full text of DOI:10.1021/ja00137a002

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