New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects

DOI: 10.1016/j.ejmech.2021.113566

Source and publish data:

European Journal of Medicinal Chemistry (2021)

Update date:2022-08-03

Topics:

Authors:

Güng?r, Tu?ba

Ozleyen, Adem

Y?lmaz, Yakup Berkay

Siyah, Pinar

Ay, Mehmet

Durda??, Serdar

Tumer, Tugba Boyunegmez

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Article abstract of DOI:10.1016/j.ejmech.2021.113566

Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and characterized by several spectroscopic techniques and primarily investigated for their inhibitory potential on COX enzymes and other pro-inflammatory factors. Experimen

Full text of DOI:10.1016/j.ejmech.2021.113566

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Product name:Methanesulfonamide, N-[2-(1-methylethoxy)-4-nitrophenyl]-

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