Bioorganic and Medicinal Chemistry Letters p. 2783 - 2786 (1998)
Update date:2022-08-05
Topics:
Sakagami, Masahiro
Horie, Kazutoshi
Nakamoto, Kazutaka
Kawaguchi, Takayuki
Hamana, Hiroshi
A novel system for active targeting of inflammattory lesions has been established. A SLe(x)-CMPul conjugate (2) showed accumulation that was 2.5- fold higher in inflammatory lesions in vivo than a SLN-CMPul conjugate (4) and 300-fold higher than monovalent SLe(x) (6).
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