Synthetic studies on trifluoroacetylindoles

DOI: 10.3987/COM-99-8480

Source and publish data:

Heterocycles p. 1119 - 1124 (1999)

Update date:2022-07-29

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Authors:

Takami, Hitoshi

Koshimura, Hirokazu

Kumazawa, Toshiaki

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Article abstract of DOI:10.3987/COM-99-8480

Trifluoroacetylindoles were obtained regioselectively through the reaction of indolylorganometallic species, prepared by halogen-metal exchange or direct metalation of N-substituted or -nonsubstituted indoles, with TFAA in good yield.

Full text of DOI:10.3987/COM-99-8480

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Product name:2,2,2-trifluoro-1-[1-di(4-fluorophenyl)methylindol-5-yl]-1-ethanone

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