Total Synthesis of (S)-(+)-Curcudiol, (S)- and (R)-(-)-Curcuphenol Based on Enzymatic Resolution of a Primary Alcohol Possessing One Stereogenic Center

Article abstract of DOI:10.1016/0957-4166(95)00229-I

A highly stereoselective synthesis of the versatile chiral synthons possessing one stereogenic center, (S)-3 and (R)-3 was achieved and the application of (S)-3 and (R)-3 into the total syntheses of (S)-curcuphenol (1), (S)-curcudiol (2), and (R)-curcuphenol (1), respectively, was described.