Rapid synthesis of [18F]SR46349B, a potent and selective 5-HT2 receptor antagonist

DOI: 10.1002/jlcr.2580360803

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 719 - 728 (1995)

Update date:2022-08-03

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Authors:

Tan Tan

Fowler Fowler

Ding Ding

Schlyer Schlyer

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Article abstract of DOI:10.1002/jlcr.2580360803

F-18 labeled SR46349B, a highly potent and selective 5-HT₂ receptor antagonist, was synthesized as a potential radioligand for PET studies of brain 5-HT₂ receptors. Nucleophilic aromatic substitution of trans-1-(2-nitrophenyl)-3-(4-m

Full text of DOI:10.1002/jlcr.2580360803

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Product name:trans-1-(2-nitrophenyl)-3-(4-methoxymethoxyphenyl)-2-propenone

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