Disaccharides as endomannosidase inhibitors: Syntheses of α-homomannojirimycin and β-homomannojirimycin linked to D-glucose and D-mannose

DOI: 10.1248/cpb.43.414

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 414 - 420 (1995)

Update date:2022-08-05

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Authors:

Suhara Suhara

Achiwa Achiwa

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Article abstract of DOI:10.1248/cpb.43.414

4-O-(α-D-Glucopyranosyl)-αHMJ (Glcα1,4HMJ), 4-O-(α-mannopyranosyl)-αHMJ (Manα1,4αHMJ), 4-O-(α-glucopyranosyl)-βHMJ (Glcα1,4βHMJ), and 4-O-(α-mannopyranosyl)-βHMJ (Manα1, 4βHMJ) were synthesized as endomannosidase inhibitors which are potentially useful both for probing the pathways of N-linked glycoprotein processing and for the chemotherapy of some viral diseases.

Full text of DOI:10.1248/cpb.43.414

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