C-Glucosylation-Cycloaddition Approach to C-Glycosyl Juglones. Versatile Intermediates toward Aryl C-Glycoside Antibiotics

Article abstract of DOI:10.1246/cl.1995.677

An efficient two-step access to C-glycosyl juglones promising synthetic intermediates toward aryl C-glycoside antibiotics, has been developed based on (1) the O->C-glycoside rearrangement and (2) the regioselective cycloaddition of α-alkoxybenzyne and α-oxyfuran.