First Synthesis of Nucleosidyl Phosphorofluoridothioates and a Convenient Synthesis of Nucleosidyl Phosphorofluoridates

Article abstract of DOI:10.1246/cl.1995.727

The first synthesis of 3'- or 5'-nucleosidyl phosphorofluoridothioates RO-P(S)(OH)F have been accomplished via nucleosidyl phosphoramidofluoridates RO-P(NPr¹2)F.An analogous convenient procedure has been employed to prepare 3'- or 5'-nucleosidy