Tetrahedron p. 12549 - 12562 (1995)
Update date:2022-08-02
Topics:
Chung, Sang J.
Kim, Dong H.
A general synthetic method for the preparation of 5,12-dihydro-5-oxobenzoxazolo<3,2-a>quinoline-6-carboxylic acids has been developed making use of the tandem double ring closure reaction of N-(2-hydroxyphenyl)anthranilic acid as the key step. 2-(4-Methylpiperazin-1-yl)-3-fluoro-5,12-dihydro-5-oxobenzoxazolo<3,2-a>quinoline-6-carboxylic acid, an oxygen isostere of a potent antibacterial, A-57,207 was thus synthesized.
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Doi:10.1039/c9cc08372c
(2020)Doi:10.1016/0040-4039(95)01409-B
(1995)Doi:10.1039/c19660000548
(1966)Doi:10.1021/jm00021a012
(1995)Doi:10.1021/jo01273a016
(1968)Doi:10.1016/0957-4166(95)00246-L
(1995)