Novel luminescent cyclometalated and terpyridine gold(III) complexes and DNA binding studies

Article abstract of DOI:10.1039/c39950001787

Two gold complexes, [Au(III){4-MeOPh-(Phbipy)}Cl]·CF₃SO₃ 1 and [Au(III)(4-MeOPh-terpy)Cl]·(ClO₄)₂ 2 [4-MeOPh-(Phbipy) = 4'-(4-methoxyphenyl)-6'-phenyl-2,2'-bipyridine, 4-MeOPh-terpy = 4'-(4-methoxyphenyl)-2,2',6',2'-terpyridine] are prepared, and their interactions with calf-thymus DNA, poly(dG-dC)₂ and poly(dA-dT)₂, investigated by spectroscopic means; in the reaction with ct DNA, 1 has a higher binding constant than 2, but the latter has a higher degree of AT specificity.

Full text of DOI:10.1039/c39950001787

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